THE JOURNAL · MONTHLY UPDATE · NOVEMBER 2026
November 2026: what changed for psilocybin in Canada.
The month’s changes to the law, clinical trials, access routes and culture around psilocybin in Canada, each with its date, what it means in plain English, and the source we read.
November 2026 edition, covering 1 to 12 November. We add to it as the month goes on. Published
Educational only, not legal or medical advice. These updates summarize public sources about psilocybin in Canada. Nothing here says what is lawful for you to do; for personal questions, speak with a regulated health care practitioner or a lawyer.
In short.
- Compass Pathways’ COMP360 study in PTSD added recruiting sites in Kamloops (5 November) and Penticton (12 November). With North Vancouver, it now lists three sites in British Columbia.
- Nothing changed in the law: no new regulations in the Canada Gazette, Bill C-286 still at first reading, and Health Canada’s psilocybin page still dated 20 October 2026.
- Compass said on 3 November that it would file the last part of its US application for COMP360 within two weeks. There is still no FDA decision, and a US decision would not change Canadian law on its own.
November 2026
Clinical trials and research
From ClinicalTrials.gov, read on 12 November 2026 and compared with our trial tracker’s October data. Of the 41 psilocybin studies with a Canadian site, only one changed after 30 October; none was added or removed, and none posted results.
COMP360 PTSD study adds recruiting sites in Kamloops and Penticton
Compass Pathways’ phase 2b/3 study of its psilocybin product COMP360 in post-traumatic stress disorder added a recruiting site in Kamloops in a record update posted on 5 November, and one in Penticton on 12 November. The same updates confirmed that the study started on 14 September 2026 and added US sites; it now lists 20 sites, three of them in British Columbia, and aims for about 300 participants. It is a company-run study, the registry names cities but not clinics, and no psilocybin product is approved in Canada.
Sources: ClinicalTrials.gov NCT07570654; ClinicalTrials.gov NCT07570654, record history: version 9 (posted 5 November 2026); ClinicalTrials.gov NCT07570654, record history: version 10 (posted 12 November 2026) · Psilocybin trial tracker for Canada
Still waiting
Checked, no change.
Things people often ask about that we checked this month and found unchanged.
- Bill C-286, a private member’s bill on psilocybin, has still had a first reading only (16 June 2026). On 12 November 2026 LEGISinfo still listed it as “Outside the Order of Precedence”. Source: LEGISinfo: Bill C-286 (45th Parliament, 1st session) · Bill C-286 explained
- Health Canada’s psilocybin page was still dated 20 October 2026 when re-read on 12 November, and still says there are no approved therapeutic products containing psilocybin. Source: Health Canada: Psilocybin and psilocin (magic mushrooms), modified 20 October 2026 · Law tracker: Canada
- No new federal rules about psilocybin: the Canada Gazette, Part I issues of 31 October and 7 November 2026 and the Part II issue of 4 November 2026 contain nothing on psilocybin, psilocin or the Controlled Substances Regulations. Source: Canada Gazette, Part I: 2026 issues · Law tracker: Canada
- Health Canada’s form for section 56 research exemptions was still dated 19 October 2026 on 12 November. Source: Health Canada: Application form for an exemption to use a controlled substance for scientific purposes, modified 19 October 2026 · Section 56 exemptions for psilocybin
- No FDA decision on COMP360 yet. Compass Pathways’ third-quarter release (3 November 2026) said the final part of its US new drug application would be filed “in the next two weeks”, with a launch expected in the first half of 2027 if the FDA approves it. A US decision would not change Canadian law on its own. Source: Compass Pathways, third-quarter 2026 results release (SEC EDGAR, 3 November 2026) · COMP360 and the FDA
- The ROM’s Psychedelics exhibition still runs until 3 January 2027 (page re-read on 12 November). Source: Royal Ontario Museum: Psychedelics: Art. Culture. Science. · The ROM’s Psychedelics exhibition: a guide